Invited Review

Vol. 5 No. 1 (2018): European Journal of Rheumatology

Semaphorin3A: A potential therapeutic tool in immune-mediated diseases

Main Article Content

Zahava Vadasz
Elias Toubi

Abstract

Abstract


 



The significance of semaphorin3A (sema3A) in regulating immune-mediated inflammation is widely reported. There are multiple mechanisms involved in the process of sema3A-mediated regulation. One of them is the ability of sema3A to maintain a sufficient regulation of both T-cell and B-cell activation. Because it is involved in the pathogenesis of many autoimmune, infectious, and malignant diseases, sema3A turns to be a promising therapeutic tool to be studied and applied in these diseases.



 



Cite this article as: Vadasz Z, Toubi E. Semaphorin3A: A potential therapeutic tool in immune-mediated disases. Eur J Rheumatol 2018; 5: 58-61.

Article Details